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Fluorescence-activating beta-barrel protein made from scratch for first time: Advance makes possible creation of new beta-barrel proteins to precisely target small molecules
For the first time, scientists have created, entirely from scratch, a protein capable of binding to a small target molecule. Researchers from the University of Washington School of Medicine report the advance in the Sept. 12 issue of the journal Nature. The ability to make such proteins from scratch, or de novo, opens the way for scientists to create proteins unlike any found in nature. These proteins can be custom-designed with high precision and affinity to bind to and act on specific small molecule targets.
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