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Central mystery of a baffling high-risk leukemia solved
St Jude Children's Research Hospital investigators have unraveled the origins and identified mutations associated with a perplexing form of acute leukemia. Their treatment is complicated because MPAL does not fit cleanly into a single diagnosis, but includes features of both acute lymphoblastic leukemia and acute myeloid leukemia. Based on the results, researchers have proposed updating the World Health Organization's classifications of acute leukemia to include three new MPAL subtypes.
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