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Among body shapes, pears are healthier than apples: Mouse study finds male obesity is linked to brain inflammation
Clinical studies have led researchers to believe females are protected against weight gain when they are young because of ovarian estrogen. We see this in mice, too; obese male mice showed nearly 50 percent decreases in testosterone and sperm number. Obesity has been associated with mental decline and an increased rate of stroke, in addition to other problems affecting the internal organs. This infiltration of peripheral immune cells into the brain occurs in addition to the activation of resident immune cells.
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