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Rare antibodies show scientists how to neutralize the many types of Ebola
A major challenge in treating what we call Ebola virus is that it isn't just one pathogen but five. For example, the Sudan and Bundibugyo viruses were responsible for 40 percent of Ebola cases before 2013, yet current experimental Ebola therapies can't neutralize them. The new research shows that antibodies that bind to a site on the viral fusion loop can neutralize all known ebolaviruses. If antibodies targeting this structure were included in therapies or elicited through vaccines, these antibodies should provide broad protection.
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